Introduction:
Anti-retrovirals "will never cure AIDS" (08 July 02, NewScientist.com news service). AIDS will never be curable using anti-retroviral drugs alone, says Robert Siliciano, an internationally renowned HIV researcher at Johns Hopkins University, Maryland.

It is common sense from a health, economic, cultural and political perspective to seek other treatments for HIV/AIDS. Those who believe that African medicinal plants have little or nothing to offer in the battle against HIV/AIDS are grossly misinformed. Principally, African herbal medicine is in the forefront of new research against this scourge. Worldwide, there is a growing trend towards herbal medicines as a supplement and/or treatment for HIV/AIDS.

Culture:
Emingeni Medicines cc aims to correct past misinformation due to ignorance and greed on the subject of African herbs and medicines. Just as important and of great significance, it separates fact from fiction. “Orthodox” education and propaganda has done much to discredit our heritage and culture. African herbs are often associated with witchcraft. This has to be corrected as a priority, if we are to achieve the progress and international acceptability and respectability that the Asian, European and other cultures have already achieved with their herbs.

Of great consequence is the fact that African herbs are already being widely used in Asia, Europe and America. In South Africa, there is a trend within all cultures to supplement present HIV/AIDS treatments with herbs and more patients are taking these products as a treatment rather than a supplement for HIV/AIDS and opportunistic diseases that accompany it.

Background:
Tr./Dr. R de Carvalho started a HIV/AIDS study in Mozambique during 1996 with the objective of providing support as well as identifying affordable and effective indigenous medicines for people living with HIV/AIDS. By 1999 a formula, Impi, had been developed using African medicinal plants for the treatment of HIV and other symptoms commonly encountered in HIV/AIDS patients. In conjunction with other traditional healers (J. Ngome, A. Chambale) and with the help of Siga Pono, Pride was later developed to further enhance the effectiveness of indigenous remedies for HIV/AIDS patients.

Some of the plants used have already been scientifically proven to have properties for HIV. Tests and studies have been carried out in the USA and Japan by scientific institutions and doctors (see page 3). Presently a study on these remedies is being done by Emingeni Medicines in conjunction with medical doctors and traditional healers to further assess the effectiveness of these herbal medicines on HIV/AIDS patients.

Safety and toxicity:
All Emingeni Medicines cc products are generally regarded as safe on the basis of a long history of safe use in Southern Africa. Usage is supported by reported scientific indications of therapeutic properties. No untoward effects have been observed in the past four years.

Emingeni Medicines cc Study

1. Methods:
All patients attending a research study being conducted by Emingeni Medicines cc have been tested positive for HIV. Tr./Dr. R. de Carvalho first assesses patients. Standard herbal medication for opportunistic infections is made available and patients are referred to Dr. Mbobo for further testing. Recorded details of when and why a HIV test was undertaken and details of living conditions i.e. employment, number of children, health status of partners and means of support are taken. Records are also kept of patient-perceived reactions to the herbal medication. Patients must attend regularly and the need for compliance program rules is explained. All patients are given Pride and Impi.

2. Documented Results
Data and anecdotal evidence from laboratories, doctors and health workers of patients using Pride and Impi is extraordinary. The terminally ill have returned to work and emaciated patients have gained weight. Over 90% of patients have recorded increased CD4 count levels and lower viral loads. Significantly, some patients have recorded undetectable viral loads.

3. Weight Changes
Significant and often sustainable gains in weight have been recorded. Some patients showed weight losses, which could often be attributed to infection or re-infection with TB.

4. Reported Patient Perceived Improvements
Visual improvements are detectable within 2-3 weeks after taking Pride and Impi. Improved appetite, energy and general well-being levels were attributed to the use of the products. Improvements are often dramatic and rapid in skin complaints, including Herpes zoster, infected scabies, abscesses and anal/genital sores and itchy rashes and can be attributed to the use of the products.

5. Other Recorded Improvements

  • Relief in respiratory problems (TB, cough, shortness of breath) is attributed to X-TB and/or TB tea.
  • Relief in diarrhoea and vomiting is attributed to No Diarrhoea Tea.
  • Improvements in energy and stamina are attributed to Bio Energy.

  • Although some of the above conditions are chronic and recur, many patients feel able to control them themselves with the medication offered and request repeats when needed.

    6. Conclusion
    The herbal treatments offered by Emingeni Medicines cc address many ailments experienced by HIV/AIDS sufferers and shows a significant improvement in quality of life in both non-wasted and terminal patients. It is appropriate for further development in home-based care and in hospital and industrial clinics. A formal pilot study to confirm our observations and records of therapeutic benefits and anecdotal evidence of raised CD4 counts and lower viral loads in patients taking Pride and
    Impi
    is urgently needed. This would serve to promote the use of our valuable natural resources more widely.

    In rural areas where there is little access to clinics and care facilities are limited, training of health workers and care givers and the development of home or community growing would have a beneficial impact. Protocols need to be developed for training purposes.

    Lack of compliance and adequate nutrition are problems related to the poverty experienced by the majority of our patients. Other social problems needing to be addressed include stigmatisation and lack of education.

    A. arborescens & AIDS Research:

    Various AIDS studies were completed by researchers such as Dr. Terry Pulse, M.D., Dr. Reg McDaniel, M.D., Dr. Terry Watson, D.O., Dr. Clumeck, M.D. (of Belgium) and others throughout the 1980’s using oral mucopolysaccharides. The results were impressive, demonstrating in many of the studies an average of 70% improvement in symptoms and laboratory criteria within 3 to 4 months. Many patients stated that opportunistic infections had stopped and they were able to return to normal activity. In one dramatic case, a man with advanced AIDS had 17 liver tumours and after one and a half years on oral Aloe mucopolysaccharides, his T-Cell count was normal and all the tumours had dissolved (confirmed by x-ray films).

    Lab studies showed that helper lymphocytes (CD4) rose to three times the pre-treatment levels. HIV-1 virus could no longer be cultured. P-24 antigen levels for the virus dropped or became negative.

    Researchers at Vanderbilt Medical Centre in Nashville, Tennessee discovered that mucopolysaccharides alters synthesis and thus the structure of the AIDS virus envelope necessary for infecting lymphocytes. Further studies at The Southern Research Institute found that there is suppression of the viral messenger RNA in HIV-1 infected leukocytes. Therefore, the reproduction of HIV-1 is inhibited with a natural and non-toxic substance.

    In studies completed at the Fort Worth Medical Centre Complex, it was demonstrated that a person’s leukocytes were rendered resistant to HIV-1 virus in culture tests outside the body.

    Substance Boosts Therapeutic Effects of AZT
    Texas A & M University
    Aids Weekly August 5, 1991 p2 (2)
    A team of scientists from Texas A&M University, College Station, and three other institutions says that a complex carbohydrate compound purified from the asphodel family appears to help drugs such as azidothymidine (AZT) and acyclovir (ACY) block the pathology associated with HIV and herpes simplex virus (HSV). They also found that the compound interfered with HIV’s ability to reproduce in infected cells. “It’s not going to be a magic bullet against AIDS,” cautions Dr. Maurice C. Kemp, a virologist in Texas A & M’s College of veterinary medicine. “There aren’t many magic bullets out there. But as an adjunctive therapy, it looks like it can be used in combination with other therapies.” The scientists’ findings are published in the July 1991, issue of the new Journal Molecular Biotherapy.

    Purification of Active Substances of A. arborescens Miller & Their Biological & Pharmacological Activity
    Saito, Hiroko, Dep. Pharm., Aichi Cancer Centre
    Phytother Res. (1993) 7 (Spec. Issue, Proceedings of the International Congress of Phytotherapy, 1991), S14-S19
    The authors purified Aloctin A from A. arborescens Miller and defined its chemical, biological and pharmacological activities. Aloctin A consists of two discrete bands, a and b with a combined S-S bond. Its molecular weight for a is 7500 and the molecular weight for b is 10,500. Aloctin A has many biological and pharmacological activities defined as follows:

    1. Hemagglutinating activity;
    2. Cytoagglutinating activity;
    3. Mitogenic activity of lymphocytes;
    4. ppt. - forming reactivity with a2-macroglobulin;
    5. Complement C3 activating activity;
    6. Inhibition of heat-induced hemolysis of rat erythrocytes;
    7. Anti-tumour effect;
    8. Anti-inflammatory effect;
    9. Inhibition of gastric secretion and gastric lesions.


    Prepared by Tr./Dr. R de Carvalho for Emingeni Medicines cc

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